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Why is hormonal treatment used in IVF ?

In an IVF trial, the menstrual cycle is stimulated by administering certain hormones.

To increase the chances of success, the hope is to be able to replace more than one embryo into the uterus. Since in a normal cycle, only one mature oocyte is usually produced, in IVF, ovaries are artificially stimulated in order to enable us to retrieve several oocytes. This procedure increases the chances of obtaining fertilized eggs and good quality embryos to be replaced into the womb.

In order to freely control and manipulate the cycle, certain secretions of the pituitary gland (located under the brain) will have to be temporarily suppressed in order to avoid parasitic hormonal interference on ovarian function. This is achieved by administering a specific inhibitor of these secretions starting at day 5 of the cycle.

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CHU Saint-Pierre, Université Libre de Bruxelles
UMC Sint-Pieter, Vrije Universiteit Brussel
Saint-Pierre University Hospital, Free University of Brussels